The shock of the season saw Barca suffer their first league loss since going down 2-0 to Malaga on April 8, 2017, ending an incredible, record-breaking sequence that had lasted 43 games.
Holders Barcelona crashed out of the Champions League after being stifled by a brilliantly well-organised Atletico Madrid.
Barcelona capitalised on two disastrous own goals by A S Roma to thrash the Italian side 4-1 at the Nou Camp on Wednesday and take a huge step towards reaching the Champions League semi-finals for the first time in three years.
Champions Barcelona suffered their second defeat in three matches in La Liga on Saturday, with Michael Krohn-Dehli scoring and setting up another goal in a 2-1 victory for Sevilla.
The draw means second-placed Atletico Madrid could close the 12-point gap with Barcelona, who are on 74 points, if they beat Celta Vigo later on Saturday.
Real Madrid and Atletico each slipped 10 points behind La Liga leaders Barcelona after an intense Madrid derby finished goalless and the Catalans picked up an 11th victory in 12 games by winning 3-0 at Leganes.
Two goals from Thomas Mueller and one from substitute Mario Goetze helped Bayern Munich kick off their Champions League campaign with an impressive 3-0 victory over Olympiakos.
Barcelona's Neymar struck twice to put the Spanish side in the Champions League final despite a 3-2 loss at Bayern Munich on Tuesday as they progressed 5-3 on aggregate and will face Real Madrid or Juventus next month.
World champions Germany drew 1-1 with Spain in a high tempo friendly on Friday as they launched their preparations for a title defence in Russia while their opponents had striker Diego Costa making his long-awaited comeback as a substitute.
IMAGES from football matches played across leagues in Europe on Sunday.
IMAGES from the Champions League quarter-final played between Barcelona and Bayern Munich in Lisbon on Friday.
Cristiano Ronaldo and Gareth Bale both scored as Real Madrid staged a remarkable late comeback from two goals down to win 3-2 at Villarreal and stay top of La Liga.
Pierre-Emerick Aubameyang scored his first three goals for Barcelona in a 4-1 win at Valencia, but Inter Milan suffered a shock 2-0 home defeat by Sassuolo. Images from the football matches played on Sunday.
IMAGES from football matches played across Europe on Sunday.
Hazard extra-time goal sends 10-man Real Madrid through to Copa del Rey final.
A summary of Wednesday night's action in the UEFA Champions League.
A summary of the opening day's action in the UEFA Champions league on Tuesday.
Real Madrid talisman Cristiano Ronaldo and Barcelona striker Luis Suarez took centre stage on Saturday in bailing their teams out with late strikes to silence their critics following slow starts to the season.
Lionel Messi scored one penalty and missed another as his double helped Barcelona sweep Levante aside in the second half in a 4-1 victory on Sunday to maintain their perfect La Liga start.
Atletico Madrid won the La Liga title for the first time since 2014
A summary of Tuesday's Group stage matches in the UEFA Champions League.
Leaders Barcelona and Real Madrid were held to draws while Sevilla made up ground on the top two and Alaves slipped after a promising start. Here are five talking points from the weekend's La Liga action.
Barcelona completed one of the most extraordinary comebacks in European football history to knock Paris St Germain out of the Champions League on Wednesday with a 6-1 victory that rewrote the record books.
Paris St Germain made light of the absent Zlatan Ibrahimovic and a sub-standard start to the season to claim a 3-2 Champions League victory over Barcelona on Tuesday.
Cristiano Ronaldo shrugged off the boos of his own supporters to fire Real Madrid to a 3-0 win over Real Sociedad on Sunday.
An under-strength Barcelona got their Champions League campaign off to a solid if unspectacular start when Gerard Pique's header secured a laboured 1-0 win at home to APOEL in their Group F opener on Wednesday.
IMAGES from the Champions League 2nd semi-final first leg match between Barcelona and Liverpool at Nou Camp on Wednesday
Messi, who has struggled for form in recent weeks due to a niggling injury, looked on a mission to grab the winner and after twice coming close he completed his treble to put Barca ahead in the 85th minute, reacting quickly to a poor Sevilla clearance to dink the ball over goalkeeper Tomas Vaclik.
Images from the international friendly and Euro qualifying football matches played on Tuesday.
Barcelona forwards Ousmane Dembele and Lionel Messi fired the Catalans to a confidence-boosting 2-0 win at in-form Sevilla on Saturday to keep the pressure on La Liga leaders Atletico Madrid.
Serge Gnabry scored twice as Bayern Munich beat Chelsea 3-0, while Antoine Griezmann's second-half equaliser handed Barcelona a vital away goal and earned them a 1-1 draw at Napoli in their Champions League last 16, first leg on Tuesday.
A round-up of Wednesday's action in the UEFA Champions League.
Barcelona wasted a golden opportunity to extend their lead at the top of LaLiga as they were shocked 1-0 at lowly Almeria on Sunday thanks to a first-half strike by El Bilal Toure.
Images from Tuesday's action in the UEFA Champions League.
Alaba strike on Clasico debut gives Real Madrid 2-1 win at Barcelona.
Germany eased into the Confederations Cup semi-finals with a 3-1 win over Cameroon on Sunday as the VAR system was again thrust into the spotlight when the on-field official needed two reviews of an incident to reach the right verdict.
A round of Wednesday night's Champions League group stage matches.
Manchester City suffered from deja vu as Luis Suarez's double gave Barcelona a 2-1 first leg lead in a Champions League last 16 tie at the Etihad although Lionel Messi's late penalty miss left the door ajar on Tuesday.
Barcelona forward Ousmane Dembele scored twice and produced a mesmerising display to fire his side to a 5-1 win over Villarreal on Wednesday which stretched the champions' unbeaten run this season to 36 games with two remaining.